Table 1 - extract terminal body weight and all absolute and relative organ weights (for each organ, absolute weights are listed on top, relative weights are shown beneath those). Also create endpoints for organs not reported in the table but listed in methods as weighed and use dummy variables (assume no effects).

Food consumption - decreased in same groups that had decreased body weight - use dummy variables

Clinical observation - increase in high dose group - use dummy variables

FOB - no effects observed - use dummy variables

Table 2 - extract all findings.

Also create endpoints for all clinical chemistry, hematology, and hormone endpoints that are not shown in Table 2 and use dummy variables to show no treatment-related effects.

Irregular Estrous Cycle - statement in text - use dummy variables to show treatment related increases in 30 and 100 mg/kg/day groups.

Estrous Cycle Length - statement in text - use dummy variables (all 0) to show no significant changes but copy and paste statement about non-significant increase into results notes.

Table 3 - extract the incidence of rats with ≥6 Days of Diestrus (0, 0, 1, 2 for control, 10, 30, 100 mg/kg/day, respectively) and indicate treatment-related increase at 30 and 100 mg/kg/day (it is not clear if this was statistically significant)

Cauda Epididymis Sperm Count, Sperm Morphology - qualitative statement of no effects - use dummy variables

Large Intestine, Dilatation of Intestinal Lumen - incidence is only reported for high dose groups, so we can't extract quantitatively - use dummy variables for all groups to show increase in high dose groups (male and female) and copy and paste statement into results notes (this is gross pathology, not histopathology, so use Gastrointestinal > Large Intestine > Clinical Observation > Abnormal Appearance as the ontology)

Table 4 - histopathology: extract all lesions except for "organs in thoracic cavity" finding. Leave sample size blank for groups not examined.

Also create general histopathology, abnormal endpoints for all organs that were examined but not represented in Table 4 and use dummy variables (all 0) to show no treatment-related changes.

Male Crj:CD (SD) Rats