GD7-16 Inhalation Developmental

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Extract the nominal concentrations as the doses in ppm and use those for conversion to doses in mg/m3. Also extract the mean analytical concentrations as another dose representation with the unit 'ppm (analytical)'.

Copy text describing the results for the specific endpoint you are extracting and paste it into results notes for each endpoint.

Extract all health endpoints that are reported in methods and/or results including:

P0 Endpoints

Clinical observation - use dummy variables, no changes from control

Maternal body weight change (GD7-16) - use dummy variables, no changes from control

Maternal food consumption - use dummy variables, no changes from control

Litter size - extract quantitatively from text on p. 3 (mean number of pups per litter, variance not reported) - no changes from control.

F1 Male/Female combined endpoints

Body weight, birth (5211) - use dummy variables, no changes from control.

Body weight change, pup (5213) - extract quantitatively (percentage of pup weight gain PND1-5 reported on p. 3). Indicate 50,000 ppm as LOAEL.

Offspring survival (3110) - extract quantitatively (percentage of pup survival PND1-5 reported on p. 3). Indicate 50,000 ppm as LOAEL.

F1 Male and Female Alderley Park Rats