Unnamed Report (2017a) (ECHA summary), 5701139

Study evaluation

Animal bioassay experiments

NameTypeComments
Repeat Dose Oral Rats (with Repro/Dev Screen) Subchronic (30-90 days)

TEST ANIMALS - Source: Charles River, Germany - Females (if applicable) nulliparous and non-pregnant: yes - Age at study initiation: 10-11 weeks old - Weight at study initiation: males: 261 - 301 g; females: 174 - 203 g - Fasting period before study: none - Housing: - Animals were housed in groups of 2 animals / sex / cage in IVC cages during the premating period for both males and females and during postmating period for males depending on the mating status. - Diet (e.g. ad libitum): Altromin 1324 maintenance diet for rats and mice, ad libitum - Water (e.g. ad libitum): Tap water, sulphur acidied to a pH of approximately 2.8, ad libitum - Acclimation period: 6 days DETAILS OF FOOD AND WATER QUALITY: Certicates of food, water and bedding are led for two years at BSL Munich and afterwards archived at Eurons Munich ENVIRONMENTAL CONDITIONS - Temperature (°C): 22 +/- 3°C - Humidity (%): : 55 +/- 10% - Air changes (per hr): 10 x / hour - Photoperiod (hrs dark / hrs light): 12 hours light, 12 hours dark 


The report refers to the test substance as triethyoxy(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)silane