ECHA 2008, 6385530
Study evaluation
Animal bioassay experiments
Name | Type | Comments |
---|---|---|
5-Day Inhalation | Short-term (1-30 days) | The report refers to the test substance as 1,1,2,2,3,3,4,4-octafluoro-1,4-diiodobutane (one of the synonyms in the PFAS Synonym List). The DTXSID# was not in the HAWC system (the Extractor added it). The chemical purity was not reported. "Test guideline Qualifier: equivalent or similar to Guideline: OECD Guideline 412 (Subacute Inhalation Toxicity: 28-Day Study) Deviations: yes Remarks: see below Principles of method if other than guideline: The exposure period was shortened to 5 days. Indeed, the purpose of this 5-day dose range finding inhalation toxicity study was to evaluate the range of toxicity, to indicate potential target organs (if any) associated with the exposure of the test substance when administered to rats by whole-body inhalation for 6 hours/day for 5 consecutive days. The results were used to select the dose levels for a subsequent 28-day toxicity study. GLP compliance: yes Limit test: no" |